PREVALENCE AND CAUSES OF RECURRENT PEPTIC ULCER

Clinical Manifestations, Causes and Management Strategies of Peptic Ulcer Disease

Peptic ulcer embraces both gastric and duodenal ulcers and has been a major threat to the world’s population over the past two centuries, with a high morbidity and substantial mortality. Discovery of gastric mucosa infection with Helicobacter pylori (H. pylori) and its association with chronic antral gastritis and peptic ulcer revolutionized the treatment of ulcer illness. H. pylori are causall...

Endoscopic diagnosis of recurrent peptic ulcer due to retained antrum.

Recurrent, peptic ulcer following surgery has a 3% to 10% recurrence rate. Recurrence is due to one of the following causes: incomplete vagotomy, failure of gastric drainage, inadequate gastric resection, Zollinger-Ellison syndrome, hyperplasia of the antral gastric-secreting cells or due to use of nonabsorbable sutures. Lack of or incomplete vagotomy has been the most common cause. Gastric ulc...

Intravenous esomeprazole for prevention of recurrent peptic ulcer bleeding.

BACKGROUND Use of proton-pump inhibitors in the management of peptic ulcer bleeding is controversial because discrepant results have been reported in different ethnic groups. OBJECTIVE To determine whether intravenous esomeprazole prevents recurrent peptic ulcer bleeding better than placebo in a multiethnic patient sample. DESIGN Randomized trial conducted between October 2005 and December ...

The problem of recurrent peptic ulcer after operation.

General Considerations Although little enough is known about the cause of the onset of duodenal ulceration, there is no doubt that its persistence is associated with increased acidity of the gastric juice. This is a physical character of the individual, based upon an excess of acid-secreting mucosa in the stomach. Failure to reduce this acidity is the chief cause of post-operative ulceration at...

Peptic Ulcer